• Brightness on Fluorescent Probes Used to Monitor Biological Activities of Individual Proteins Increased

• High Definition Diagnostic Ultrasonics on the Nanoscale

• Magnetic Molecular Machines Deliver Drugs to Unhealthy Cells

• Breakthrough in Blinking Molecules Phenomenon

• Optical Imaging Technique for Angioplasty

• Molecular Imaging Identifies High-Risk Patients With Heart Disease

• Scientists Achieve Highest-Resolution MRI of the Inside of a Magnet

• Spectral Molecular Imaging, Inc. to Develop a New Generation of Multispectral Imaging Endoscopes Based on Optical Technology from Omega Optical

• SurgiVision Announces First Patient Procedure Using the ClearPoint System

• New Cardiac Imaging Device Pioneered

• A Waste of Time?

• NCI's SBIR Initiatives Aiming to Strengthen Startup Support

• Novel Bee Venom Derivative Forms a Nanoparticle 'Smart Bomb' to Target Cancer Cells

• New Imaging Technique Could Help Physicians Ease the Aftermath of Breast Cancer

• Latest Findings in CT Radiation Dose Reduction Efforts

• Iron Oxide Nanoparticles Becoming Tools for Brain Tumor Imaging and Treatment

• Fluorescent Biosensor to Aid in Drug Development

• Functional Magnetic Resonance Imaging to Evaluate Pancreatic Cancer

• Multifunctional Nanoparticle Enables New Type of Biological Imaging

• Engineered Coral Pigment Helps Scientists to Observe Protein Movement

• GenSpera Acquires Rights to Cancer Imaging Technology to Create a New Generation of Medical Imaging Tools for Oncologists

• PerkinElmer to Acquire VisEn Medical, Inc.

•  CEA-Leti’s New Imaging System for fDOT Ready for Commercialization, Use in Measuring and Treating Cancer 

• St. Jude Medical Completes Acquisition of LightLab Imaging

• SonoSite Completes Acquisition of VisualSonics

• Noninvasive MR Imaging of Blood Vessel Growth in Tumors Using Nanosized Contrast Agents

• Turning Back the Cellular Clock: Method Developed for Tracking Adult Stem Cells as They Regress

• Nanoparticles as Destructive Beacons to Zap Tumors

• How Do Cells Die? Biophotonic Tools Reveal Real-Time Dynamics in Living Color

• Replacing Hydrogen in Fluorescent Dyes Improves Detection Ability, Stability and Shelf Life

• High-Speed Study of Zebrafish Larvae: New Technique Can Analyze Larvae in Seconds

• Scientists Create Army of Tumor-Fighting Immune Cells and Watch as They Attack Cancer

• Mice Cages Can Alter Rodents’ Brains and Skew Research Results, Study Finds

• AVEO Pharmaceuticals’ Human Response Platform™ and Proprietary Mouse Models Featured in Nature Reviews Cancer

• To Predict Atherosclerosis, Follow the Disturbed Blood Flow

• Nanoparticles Shrink Tumors in Mice

• Smaller tags cure the GFP blues

• Researchers reduce risk of teratomas from stem cell transplants

• Optical imaging could create pathway for radiotracers, study finds

• Radioactive optical imaging and 'quantum dot' nano-imaging at the forefront of molecular medicine

• Molecular imaging 'probes' pinpoint prostate cancer

• Important advance in imaging of cell death

• Molecular imaging prototype looks deep into soft tissues of the brain and other organs

• Nanoparticles: Peering into the never-before-seen

• Consumer-grade camera detects cancer cells in real time

• Hallmark Alzheimer's disease changes found in retinas of humans and imaged in live animals

• Feast and famine: MRI reveals secrets of animal anatomy

• 'Digital embryo' gains wings: Now possible to film development of fruit fly and of zebrafish's eyes and brain

• Scientists create 3-D models of whole mouse organs

• Circadian clock in pancreas directly linked to diabetes

• Bursting bubbles with sound offers new treatments for cancer

• Piglets open doors to study infant brain development

• The Next Generation Of Imaging Techniques Could Harness A Technology That Moves Faster Than The Speed Of Light

• Color-coded T cells illuminate immune response

• Embryogenesis imaging just got sweeter, thanks to glycans

• MagForce Nano-Cancer Therapy

• The Ultimate Telemedicine Tweak to dSLRs: Cancer Detection

• GE Gets Grant For New Fluorescent Nerve Imaging System

• OCT Intravascular Imaging System

• Fluorescent Compounds Make Tumors Glow

• Molecular Structure of Key Fluorescent Proteins

• Transplanted Adult Stem Cells Help Injured Hearts

• Molecular Imaging of IGF-1R in Breast Cancer

• Ultrasensitive imaging with gold-silver 'nanocages'

• Pluripotent stem cells create first living animal

• Another 13 stem cell lines approved

• Fluorescent molecules tag tumors early

• Nanoparticles Spot Residual Tumors, Improve Surgery

• Nanodiamonds Significantly Improve MRI Contrast

• Blinking neurons give thoughts away

Nanobodies: going single domain

Conventional antibodies are not suitable for in vivo studies, which has limited some applications in basic research, therapeutics, and diagnostics. Andrew Wiecek investigates how camel, llama, and shark antibodies are being used to overcome this limitation.

Study finds how nanoparticles indirectly damage DNA in cells

British researchers who built a multi-layer "barrier" of human cells to replicate the function of specialized protective tissues in the body found that signals transmitted by nanoparticles through the protective barrier indirectly damage DNA inside cells. The study results "expand significantly the hurdles that any theoretical nano-safety assessment would need to clear," an expert said. The discovered mechanism, however, also opens up the possibility of being able to deliver treatments across barriers without actually crossing them, another expert suggested.

Canary Funds Early Cancer Center at Stanford

NEW YORK (GenomeWeb News) – Stanford University will use a $15 million commitment from the Canary Foundation, along with $5 million of its own funds, to start a cancer research center focused on using proteomics and imaging techniques to find ways to identify cancer earlier.

Preclinical Drug Development Must Consider the Impact on Metastasis

Drs. Steeg et al., President and members of the "Metastasis Research Society " propose that preclinical anticancer drug development be required to show efficacy in at least one metastasis model, preferably incorporating metastasis from an orthotopic site.  Robust models are available with relevant histology and Imaging for quantification.

Clin Cancer Res 2009; 15 (14) July 15, 2009

Infrared-fluorescent proteins for whole body imaging

2008 Nobel-Prize winner Roger Tsien, Ph.D., has engineered infrared-fluorescent proteins (IFPs) that are are suitable for whole-body imaging in small animals.

The 2009 Lindau Nobel Laureate Meeting: Roger Y. Tsien, Chemistry 2008 (Jove video)